Structure of PDB 1qfc Chain A Binding Site BS02

Receptor Information
>1qfc Chain A (length=287) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TAPASTLRFVAVGDWGGVPNAPFHTAREMANAKEIARTVQIMGADFIMSL
GDNFYFTGVHDANDKRFQETFEDVFSDRALRNIPWYVLAGNHDHLGNVSA
QIAYSKISKRWNFPSPYYRLRFKVPRSNITVAIFMLDTVMLCGNSVARTQ
LSWLKKQLAAAKEDYVLVAGHYPIWSIAEHGPTRCLVKNLRPLLAAYGVT
AYLCGHDHNLQYLQDENGVGYVLSGAGNFMDPSVRHQRKVPNGYLRFHYG
SEDSLGGFTYVEIGSKEMSITYVEASGKSLFKTSLPR
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain1qfc Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1qfc Crystal structure of a mammalian purple acid phosphatase.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		D14 D52 Y55 H223
Binding residue
(residue number reindexed from 1)		D14 D52 Y55 H208
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.2: acid phosphatase.
Gene Ontology
Molecular Function
GO:0003993 acid phosphatase activity
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:1qfc, PDBe:1qfc, PDBj:1qfc
PDBsum1qfc
PubMed10388567
UniProtP29288|PPA5_RAT Tartrate-resistant acid phosphatase type 5 (Gene Name=Acp5)

[Back to BioLiP]