Structure of PDB 1q1u Chain A Binding Site BS02

Receptor Information
>1q1u Chain A (length=138) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVA
IQGVKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQ
ESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEV
Ligand information
Ligand IDSO4
InChIInChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
InChIKeyQAOWNCQODCNURD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-]S(=O)(=O)[O-]
CACTVS 3.341[O-][S]([O-])(=O)=O
ACDLabs 10.04[O-]S([O-])(=O)=O
FormulaO4 S
NameSULFATE ION
ChEMBL
DrugBankDB14546
ZINC
PDB chain1q1u Chain A Residue 440 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1q1u Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs
Resolution1.7 Å
Binding residue
(original residue number in PDB)		Y72 K123 R126
Binding residue
(residue number reindexed from 1)		Y67 K118 R121
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008083 growth factor activity

View graph for
Molecular Function
External links
PDB RCSB:1q1u, PDBe:1q1u, PDBj:1q1u
PDBsum1q1u
PubMed12815063
UniProtP61328|FGF12_HUMAN Fibroblast growth factor 12 (Gene Name=FGF12)

[Back to BioLiP]