Structure of PDB 1oyo Chain A Binding Site BS02
Receptor Information
>1oyo Chain A (length=279) Species:
37998
(Parengyodontium album) [
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AAQTNAPWGLARISSTSPGTSTYYYDESAGQGSCVYVIDTGIEASHPEFE
GRAQMVKTYYYSSRDGNGHGTHCAGTVGSRTYGVAKKTQLFGVKVLDDNG
SGQYSTIIAGMDFVASDKNNRNCPKGVVASLSLGGGYSSSVNSAAARLQS
SGVMVAVAAGNNNADARNYSPASEPSVCTVGASDRYDRRSSFSNYGSVLD
IFGPGTSILSTWIGGSTRSISGTSMATPHVAGLAAYLMTLGKTTAASACR
YIADTANKGDLSNIPFGTVNLLAYNNYQA
Ligand information
Ligand ID
3ID
InChI
InChI=1S/C8H7NO2/c10-7-3-5-1-2-9-6(5)4-8(7)11/h1-4,9-11H
InChIKey
SGNZYJXNUURYCH-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
Oc1cc2c(cc1O)ncc2
OpenEye OEToolkits 1.5.0
c1c[nH]c2c1cc(c(c2)O)O
CACTVS 3.341
Oc1cc2[nH]ccc2cc1O
Formula
C8 H7 N O2
Name
3H-INDOLE-5,6-DIOL
ChEMBL
CHEMBL92636
DrugBank
DB01811
ZINC
ZINC000000895800
PDB chain
1oyo Chain A Residue 694 [
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Receptor-Ligand Complex Structure
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PDB
1oyo
Regulation of protease activity by melanin: Crystal structure of the complex formed between proteinase K and melanin monomers at 2.0 resolution
Resolution
2.02 Å
Binding residue
(original residue number in PDB)
H69 L96 S132 L133 G134 S224
Binding residue
(residue number reindexed from 1)
H69 L96 S132 L133 G134 S224
Annotation score
1
Enzymatic activity
Catalytic site (original residue number in PDB)
D39 H69 N161 S224
Catalytic site (residue number reindexed from 1)
D39 H69 N161 S224
Enzyme Commision number
3.4.21.64
: peptidase K.
Gene Ontology
Molecular Function
GO:0004252
serine-type endopeptidase activity
GO:0008236
serine-type peptidase activity
Biological Process
GO:0006508
proteolysis
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Molecular Function
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Biological Process
External links
PDB
RCSB:1oyo
,
PDBe:1oyo
,
PDBj:1oyo
PDBsum
1oyo
PubMed
UniProt
P06873
|PRTK_PARAQ Proteinase K (Gene Name=PROK)
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