Structure of PDB 1ovt Chain A Binding Site BS02

Receptor Information
>1ovt Chain A (length=682) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVIRWCTISSPEEKKCNNLRDLTQQERISLTCVQKATYLDCIKAIANNEA
DAISLDGGQAFEAGLAPYKLKPIAAEVYEHTEGSTTSYYAVAVVKKGTEF
TVNDLQGKTSCHTGLGRSAGWNIPIGTLLHRGAIEWEGIESGSVEQAVAK
FFSASCVPGATIEQKLCRQCKGDPKTKCARNAPYSGYSGAFHCLKDGKGD
VAFVKHTTVNENAPDQKDEYELLCLDGSRQPVDNYKTCNWARVAAHAVVA
RDDNKVEDIWSFLSKAQSDFGVDTKSDFHLFGPPGKKDPVLKDLLFKDSA
IMLKRVPSLMDSQLYLGFEYYSAIQSMRKDQLTPSPRENRIQWCAVGKDE
KSKCDRWSVVSNGDVECTVVDETKDCIIKIMKGEADAVALDGGLVYTAGV
CGLVPVMAERYDDESQCSKTDERPASYFAVAVARKDSNVNWNNLKGKKSC
HTAVGRTAGWVIPMGLIHNRTGTCNFDEYFSEGCAPGSPPNSRLCQLCQG
SGGIPPEKCVASSHEKYFGYTGALRCLVEKGDVAFIQHSTVEENTGGKNK
ADWAKNLQMDDFELLCTDGRRANVMDYRECNLAEVPTHAVVVRPEKANKI
RDLLERQEKRFGVNGSEKSKFMMFESQNKDLLFKDLTKCLFKVREGTTYK
EFLGDKFYTVISSLKTCNPSDILQMCSFLEGK
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain1ovt Chain A Residue 689 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1ovt Crystal structure of diferric hen ovotransferrin at 2.4 A resolution.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		D395 Y431 Y524 H592
Binding residue
(residue number reindexed from 1)		D391 Y427 Y520 H588
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0008199 ferric iron binding
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0006880 intracellular sequestering of iron ion
GO:0006881 extracellular sequestering of iron ion
GO:0006953 acute-phase response
GO:0009410 response to xenobiotic stimulus
GO:0019730 antimicrobial humoral response
GO:0019731 antibacterial humoral response
GO:0032496 response to lipopolysaccharide
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0055037 recycling endosome
GO:1990377 organomineral extracellular matrix

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ovt, PDBe:1ovt, PDBj:1ovt
PDBsum1ovt
PubMed7490743
UniProtP02789|TRFE_CHICK Ovotransferrin

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