Structure of PDB 1obd Chain A Binding Site BS02

Receptor Information

>1obd Chain A (length=298) Species: 4932 (Saccharomyces cerevisiae)

SITKTELDGILPLVARGKVRDIYEVDAGTLLFVATDRISAYDVIMENSIP
EKGILLTKLSEFWFKFLSNDVRNHLVDIAPGKTIFDYLPAKLSEPKYKTQ
LEDRSLLVHKHKLIPLEVIVRGYITGSAWKEYVKTGTVHGLKQPQGLKES
QEFPEPIFTPSTKADENISPAQAAELVGEDLSRRVAELAVKLYSKCKDYA
KEKGIIIADTKFEFGIDEKTNEIILVDEVLTPDSSRFWNGASYKVGESQD
SYDKQFLRDWLTANKLNGVNGVKMPQDIVDRTRAKYIEAYETLTGSKW

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 1obd Chain A Residue 311

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1obd The Structure of Saicar Synthase: An Enzyme in the De Novo Pathway of Purine Nucleotide Biosynthesis
• Resolution: 1.4 Å
• Binding residue (original residue number in PDB): S61 E234
• Binding residue (residue number reindexed from 1): S60 E228
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 6.3.2.6: phosphoribosylaminoimidazolesuccinocarboxamide synthase.

Gene Ontology

Molecular Function

• GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
• GO:0005515 protein binding
• GO:0005524 ATP binding
• GO:0016874 ligase activity

Biological Process

• GO:0006164 purine nucleotide biosynthetic process
• GO:0006189 'de novo' IMP biosynthetic process

Cellular Component

• GO:0005634 nucleus
• GO:0005737 cytoplasm

External links

• PDB: RCSB:1obd, PDBe:1obd, PDBj:1obd
• PDBsum: 1obd
• UniProt: P27616|PUR7_YEAST Phosphoribosylaminoimidazole-succinocarboxamide synthase (Gene Name=ADE1)