Structure of PDB 1mdm Chain A Binding Site BS02

Receptor Information
>1mdm Chain A (length=124) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI
LGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRL
LAERVCDNDTVPSVSSINRIIRTK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1mdm STRUCTURAL ANALYSIS OF THE AUTOINHIBITION OF ETS-1 AND ITS ROLE IN PROTEIN PARTNERSHIPS
Resolution2.8 Å
Binding residue
(original residue number in PDB)		N21 Q22 F27 G30 P32 L33 S61 C64 K67 P80 G81 V82 I83 G84 G85 F110 A111
Binding residue
(residue number reindexed from 1)		N3 Q4 F9 G12 P14 L15 S43 C46 K49 P62 G63 V64 I65 G66 G67 F92 A93
Binding affinityPDBbind-CN: Kd=35pM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1mdm, PDBe:1mdm, PDBj:1mdm
PDBsum1mdm
PubMed12221090
UniProtQ02548|PAX5_HUMAN Paired box protein Pax-5 (Gene Name=PAX5)

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