Structure of PDB 1lsx Chain A Binding Site BS02

Receptor Information
>1lsx Chain A (length=116) Species: 375 (Bradyrhizobium japonicum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DAMIVIDGHGIIQLFSTAAERLFGWSELEAIGQNVNILMPEPDRSRHDSY
ISRYRTTSDPHIIGIGRIVTGKRRDGTTFPMHLSIGEMQSGGEPYFTGFV
RDLTEHQQTQARLQEL
Ligand information
Ligand ID1MZ
InChIInChI=1S/C4H6N2/c1-6-3-2-5-4-6/h2-4H,1H3/p+1
InChIKeyMCTWTZJPVLRJOU-UHFFFAOYSA-O
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		Cn1cc[nH+]c1
ACDLabs 10.04c1c[nH+]cn1C
FormulaC4 H7 N2
Name1-METHYLIMIDAZOLE
ChEMBL
DrugBankDB02671
ZINC
PDB chain1lsx Chain A Residue 111 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1lsx Structure-based mechanism of O2 sensing and ligand discrimination by the FixL heme domain of Bradyrhizobium japonicum
Resolution2.7 Å
Binding residue
(original residue number in PDB)		I215 L236 I238
Binding residue
(residue number reindexed from 1)		I62 L83 I85
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:1lsx, PDBe:1lsx, PDBj:1lsx
PDBsum1lsx
PubMed12390021
UniProtP23222|FIXL_BRADU Sensor protein FixL (Gene Name=fixL)

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