Structure of PDB 1lok Chain A Binding Site BS02

Receptor Information

>1lok Chain A (length=291) Species: 671 (Vibrio proteolyticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MPPITQQATVTAWLPQVDASQITGTISSLESFTNRFYTTTSGAQASDWIA
SEWQALSASLPNASVKQVSHSGYNQKSVVMTITGSEAPDEWIVIGGHLDS
TIGSHTNEQSVAPGADDDASGIAAVTEVIRVLSENNFQPKRSIAFMAYAA
EEVGLRGSQDLANQYKSEGKNVVSALQLDMTNYKGSAQDVVFITDYTDSN
FTQYLTQLMDEYLPSLTYGFDTCGYACSDHASWHNAGYPAAMPFESKFND
YNPRIHTTQDTLANSDPTGSHAKKFTQLGLAYAIEMGSATG

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

1lok Chain A Residue 902 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1lok The 1.20 Angstrom Resolution Crystal Structure of the Aminopeptidase from Aeromonas proteolytica Complexed with Tris A tale of Buffer Inhibition
Resolution	1.2 Å
Binding residue (original residue number in PDB)	H97 D117 D179
Binding residue (residue number reindexed from 1)	H97 D117 D179
Annotation score	4

Enzymatic activity

Catalytic site (original residue number in PDB)	H97 D117 E151 E152 D179 H256
Catalytic site (residue number reindexed from 1)	H97 D117 E151 E152 D179 H256
Enzyme Commision number	3.4.11.10: bacterial leucyl aminopeptidase.

Gene Ontology

	Molecular Function
GO:0008235	metalloexopeptidase activity

	Biological Process
GO:0006508	proteolysis

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Molecular Function

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Biological Process

External links

PDB	RCSB:1lok, PDBe:1lok, PDBj:1lok
PDBsum	1lok
PubMed	12176384
UniProt	Q01693\|AMPX_VIBPR Bacterial leucyl aminopeptidase

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