Structure of PDB 1lb3 Chain A Binding Site BS02

Receptor Information

>1lb3 Chain A (length=167) Species: 10090 (Mus musculus)

SQIRQNYSTEVEAAVNRLVNLHLRASYTYLSLGFFFDRDDVALEGVGHFF
RELAEEKREGAERLLEFQNDRGGRALFQDVQKPSQDEWGKTQEAMEAALA
MEKNLNQALLDLHALGSARADPHLCDFLESHYLDKEVKLIKKMGNHLTNL
RRVASLGEYLFERLTLK

Ligand information

• Ligand ID: CD
• InChI: InChI=1S/Cd/q+2
• InChIKey: WLZRMCYVCSSEQC-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Cd++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Cd+2]
• Formula: Cd
• Name: CADMIUM ION
• PDB chain: 1lb3 Chain A Residue 720

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1lb3 Structural description of the active sites of mouse L-chain ferritin at 1.2A resolution
• Resolution: 1.21 Å
• Binding residue (original residue number in PDB): H118 C130
• Binding residue (residue number reindexed from 1): H113 C125
• Annotation score: 3

Gene Ontology

Molecular Function

• GO:0005506 iron ion binding
• GO:0005515 protein binding
• GO:0008199 ferric iron binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006826 iron ion transport
• GO:0006879 intracellular iron ion homeostasis

Cellular Component

• GO:0005576 extracellular region
• GO:0005737 cytoplasm
• GO:0005764 lysosome
• GO:0005776 autophagosome
• GO:0031410 cytoplasmic vesicle
• GO:0044754 autolysosome
• GO:0070288 ferritin complex
• GO:0071682 endocytic vesicle lumen

External links

• PDB: RCSB:1lb3, PDBe:1lb3, PDBj:1lb3
• PDBsum: 1lb3
• PubMed: 12459904
• UniProt: P29391|FRIL1_MOUSE Ferritin light chain 1 (Gene Name=Ftl1)