Structure of PDB 1kuh Chain A Binding Site BS02

Receptor Information
>1kuh Chain A (length=132) Species: 53502 (Streptomyces caespitosus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TVTVTYDPSNAPSFQQEIANAAQIWNSSVRNVQLRAGGNADFSYYEGNDS
RGSYAQTDGHGRGYIFLDYQQNQQYDSTRVTAHETGHVLGLPDHYQGPCS
ELMSGGGPGPSCTNPYPNAQERSRVNALWANG
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1kuh Chain A Residue 134 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1kuh Structure of the zinc endoprotease from Streptomyces caespitosus.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		D76 T78
Binding residue
(residue number reindexed from 1)		D76 T78
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.24.77: snapalysin.
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1kuh, PDBe:1kuh, PDBj:1kuh
PDBsum1kuh
PubMed9089404
UniProtP56406|SNPA_STRCS Extracellular small neutral protease (Gene Name=snpA)

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