Structure of PDB 1ko7 Chain A Binding Site BS02

Receptor Information
>1ko7 Chain A (length=285) Species: 1288 (Staphylococcus xylosus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLTTKSLVERFELEMIAGEAGLNKQIKNTDISRPGLEMAGYFSHYASDRI
QLLGTTELSFYNLLPDEERKGRMRKLCRPETPAIIVTRDLEPPEELIEAA
KEHETPLITSKIATTQLMSRLTTFLEHELARTTSLHGVLVDVYGVGVLIT
GDSGIGKSETALELIKRGHRLVADDNVEIREISKDELIGRAPKLIEHLLE
IRGLGIINVMTLFGAGSILTEKRLRLNIHLENEETLRILDTEITKKTIPV
RPGRNVAVIIEVAAMNYRLNIMGINTAEEFNDRLN
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain1ko7 Chain A Residue 317 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1ko7 Structure of the full-length HPr kinase/phosphatase from Staphylococcus xylosus at 1.95 A resolution: Mimicking the product/substrate of the phospho transfer reactions.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		S153 K157
Binding residue
(residue number reindexed from 1)		S153 K157
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.11.-
2.7.4.-
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0000287 magnesium ion binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0005524 ATP binding
GO:0046872 metal ion binding
Biological Process
GO:0000160 phosphorelay signal transduction system
GO:0006109 regulation of carbohydrate metabolic process
GO:0016310 phosphorylation
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1ko7, PDBe:1ko7, PDBj:1ko7
PDBsum1ko7
PubMed11904409
UniProtQ9S1H5|HPRK_STAXY HPr kinase/phosphorylase (Gene Name=hprK)

[Back to BioLiP]