Structure of PDB 1kln Chain A Binding Site BS02

Receptor Information
>1kln Chain A (length=595) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VISYDNYVTILDEETLKAWIAKLEKAPVFAFATETDSLDNISANLVGLSF
AIEPGVAAYIPVAHDYLDAPDQISRERALELLKPLLEDEKALKVGQNLKY
DRGILANYGIELRGIAFDTMLESYILNSVAGRHDMDSLAERWLKHKTITF
EEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPDLQKHKGPL
NVFENIEMPLVPVLSRIERNGVKIDPKVLHNHSEELTLRLAELEKKAHEI
AGEEFNLSSQLQTILFEKQGIKPLKTSEEVLEELALDYPLPKVILEYRGL
AKLKSTYTDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVRN
EEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRDKGLLTAFAEGKDI
HRATAAEVFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIPRKE
AQKYMDLYFERYPGVLEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSNG
ARRAAAERAAINAPMQGTAADIIKRAMIAVDAWLQAEQPRVRMIMQVHDE
LVFEVHKDDVDAVAKQIHQLMENCTRLDVPLLVEVGSGENWDQAH
Ligand information
Receptor-Ligand Complex Structure
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PDB1kln Structure of DNA polymerase I Klenow fragment bound to duplex DNA.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		N579 L580 S582 D827
Binding residue
(residue number reindexed from 1)		N256 L257 S259 D494
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication

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Molecular Function
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Biological Process
External links
PDB RCSB:1kln, PDBe:1kln, PDBj:1kln
PDBsum1kln
PubMed8469987
UniProtP00582|DPO1_ECOLI DNA polymerase I (Gene Name=polA)

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