Structure of PDB 1ki0 Chain A Binding Site BS02

Receptor Information
>1ki0 Chain A (length=253) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEE
NYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGKISK
TMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTD
PNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHW
SAQTPHTHERTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKI
PSC
Ligand information
Ligand IDBCN
InChIInChI=1S/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11)
InChIKeyFSVCELGFZIQNCK-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(CO)N(CCO)CC(=O)O
CACTVS 3.341OCCN(CCO)CC(O)=O
ACDLabs 10.04O=C(O)CN(CCO)CCO
FormulaC6 H13 N O4
NameBICINE
ChEMBL
DrugBankDB03709
ZINCZINC000001683490
PDB chain1ki0 Chain A Residue 336 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1ki0 The X-ray crystallographic structure of the angiogenesis inhibitor angiostatin.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		R117 W144 R153 Y154
Binding residue
(residue number reindexed from 1)		R37 W64 R73 Y74
Annotation score1
Enzymatic activity
Enzyme Commision number 3.4.21.7: plasmin.
External links
PDB RCSB:1ki0, PDBe:1ki0, PDBj:1ki0
PDBsum1ki0
PubMed12054798
UniProtP00747|PLMN_HUMAN Plasminogen (Gene Name=PLG)

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