Structure of PDB 1k4j Chain A Binding Site BS02

Receptor Information
>1k4j Chain A (length=193) Species: 66271 (Pantoea stewartii subsp. stewartii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMLELFDVSYEELRLGWEVICSQGMESDEFDGPGTRYILGICEGQLVCSV
RFTSLDRPNMITHTFQHCFSDVTLPAYGTESSRFFVDKARARALLGEHYP
ISQVLFLAMVNWAQNNAYGNIYTIVSRAMLKILTRSGWQIKVIKEAFLTE
KERIYLLTLPAGQDDKQQLGGDVVSRTGCPPVAVTTWPLTLPV
Ligand information
Ligand IDREO
InChIInChI=1S/4O.Re/q;;;-1;
InChIKeyWPWXHJFQOFOBAC-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[O-][Re](=O)(=O)=O
FormulaO4 Re
NamePERRHENATE
ChEMBL
DrugBank
ZINC
PDB chain1k4j Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1k4j Structural basis and specificity of acyl-homoserine lactone signal production in bacterial quorum sensing.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		C85 K161 A163 F164
Binding residue
(residue number reindexed from 1)		C68 K144 A146 F147
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.1.184: acyl-homoserine-lactone synthase.
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0061579 N-acyl homoserine lactone synthase activity
Biological Process
GO:0007165 signal transduction
GO:0009372 quorum sensing

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Molecular Function
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Biological Process
External links
PDB RCSB:1k4j, PDBe:1k4j, PDBj:1k4j
PDBsum1k4j
PubMed11931774
UniProtP54656|ESAI_PANSE Acyl-homoserine-lactone synthase (Gene Name=esaI)

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