Structure of PDB 1k12 Chain A Binding Site BS02

Receptor Information
>1k12 Chain A (length=158) Species: 7936 (Anguilla anguilla) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VIPEGYTQENVAVRGKATQSAQLRGEHAANSEASNAIDGNRDSNFYHGSC
THSSGQANPWWRVDLLQVYTITSVTITNRGDCCGERISGAEINIGQHLAS
NGVNNPECSVIGSMATGETKTFHCPAPMIGRYVVTYLPTSESLHLCEVEV
NVDKPAAA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1k12 Chain A Residue 160 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1k12 A novel fucose recognition fold involved in innate immunity.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		N35 D38 N40 S49 C146 E147
Binding residue
(residue number reindexed from 1)		N35 D38 N40 S49 C146 E147
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0030246 carbohydrate binding
GO:0042806 fucose binding
GO:0046872 metal ion binding
Biological Process
GO:0001868 regulation of complement activation, lectin pathway
GO:0010185 regulation of cellular defense response
GO:0045088 regulation of innate immune response
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1k12, PDBe:1k12, PDBj:1k12
PDBsum1k12
PubMed12091873
UniProtQ7SIC1|FUCL_ANGAN Fucolectin

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