Structure of PDB 1joc Chain A Binding Site BS02

Receptor Information
>1joc Chain A (length=123) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQ
IKHTQALNRKWAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAECSAK
NALTPSSKKPVRVCDACFNDLQG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1joc Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1joc Multivalent endosome targeting by homodimeric EEA1.
Resolution2.2 Å
Binding residue
(original residue number in PDB)
C1358 C1361 C1385
Binding residue
(residue number reindexed from 1)
C70 C73 C97
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:1joc, PDBe:1joc, PDBj:1joc
PDBsum1joc
PubMed11741531
UniProtQ15075|EEA1_HUMAN Early endosome antigen 1 (Gene Name=EEA1)

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