Structure of PDB 1jae Chain A Binding Site BS02

Receptor Information

>1jae Chain A (length=471) Species: 7067 (Tenebrio molitor)

QKDANFASGRNSIVHLFEWKWNDIADECERFLQPQGFGGVQISPPNEYLV
ADGRPWWERYQPVSYIINTRSGDESAFTDMTRRCNDAGVRIYVDAVINHM
TGMNGVGTSGSSADHDGMNYPAVPYGSGDFHSPCEVNNYQDADNVRNCEL
VGLRDLNQGSDYVRGVLIDYMNHMIDLGVAGFRVDAAKHMSPGDLSVIFS
GLKNLNTDYGFADGARPFIYQEVIDLGGEAISKNEYTGFGCVLEFQFGVS
LGNAFQGGNQLKNLANWGPEWGLLEGLDAVVFVDNHDNQRTGGSQILTYK
NPKPYKMAIAFMLAHPYGTTRIMSSFDFTDNDQGPPQDGSGNLISPGIND
DNTCSNGYVCEHRWRQVYGMVGFRNAVEGTQVENWWSNDDNQIAFSRGSQ
GFVAFTNGGDLNQNLNTGLPAGTYCDVISGELSGGSCTGKSVTVGDNGSA
DISLGSAEDDGVLAIHVNAKL

Ligand information

• Ligand ID: CL
• InChI: InChI=1S/ClH/h1H/p-1
• InChIKey: VEXZGXHMUGYJMC-UHFFFAOYSA-M
• SMILES:
  ACDLabs 10.04
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: [Cl-]
• Formula: Cl
• Name: CHLORIDE ION
• DrugBank: DB14547
• PDB chain: 1jae Chain A Residue 501

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1jae Crystal structure of yellow meal worm alpha-amylase at 1.64 A resolution.
• Resolution: 1.65 Å
• Binding residue (original residue number in PDB): R183 R321
• Binding residue (residue number reindexed from 1): R183 R321
• Annotation score: 3

Enzymatic activity

• Enzyme Commision number: 3.2.1.1: alpha-amylase.

Gene Ontology

Molecular Function

• GO:0003824 catalytic activity
• GO:0004556 alpha-amylase activity
• GO:0005509 calcium ion binding
• GO:0016798 hydrolase activity, acting on glycosyl bonds
• GO:0031404 chloride ion binding
• GO:0043169 cation binding
• GO:0046872 metal ion binding

Biological Process

• GO:0005975 carbohydrate metabolic process
• GO:0016052 carbohydrate catabolic process

Cellular Component

• GO:0005615 extracellular space

External links

• PDB: RCSB:1jae, PDBe:1jae, PDBj:1jae
• PDBsum: 1jae
• PubMed: 9600843
• UniProt: P56634|AMY_TENMO Alpha-amylase