Structure of PDB 1j2x Chain A Binding Site BS02

Receptor Information
>1j2x Chain A (length=70) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPLDVQVTEDAVRRYLTRKPMTTKDLLKKFQTKKTGLSSEQTVNVLAQIL
KRLNPERKMINDKMHFSLKE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1j2x Chain A Residue 1000 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1j2x Molecular mechanism of recruitment of TFIIF- associating RNA polymerase C-terminal domain phosphatase (FCP1) by transcription factor IIF
Resolution2.0 Å
Binding residue
(original residue number in PDB)		E503 E517
Binding residue
(residue number reindexed from 1)		E56 E70
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006367 transcription initiation at RNA polymerase II promoter
GO:0032968 positive regulation of transcription elongation by RNA polymerase II
Cellular Component
GO:0005634 nucleus

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Cellular Component
External links
PDB RCSB:1j2x, PDBe:1j2x, PDBj:1j2x
PDBsum1j2x
PubMed12591941
UniProtP35269|T2FA_HUMAN General transcription factor IIF subunit 1 (Gene Name=GTF2F1)

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