Structure of PDB 1isc Chain A Binding Site BS02

Receptor Information
>1isc Chain A (length=192) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIKGTAFEGK
SLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASF
GSFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDAT
PLLTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA
Ligand information
Ligand IDAZI
InChIInChI=1S/N3/c1-3-2/q-1
InChIKeyIVRMZWNICZWHMI-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[N-]=[N+]=[N-]
FormulaN3
NameAZIDE ION
ChEMBLCHEMBL79455
DrugBank
ZINC
PDB chain1isc Chain A Residue 195 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1isc Structure-function in Escherichia coli iron superoxide dismutase: comparisons with the manganese enzyme from Thermus thermophilus.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		H26 H30 H31 Y34 H73 H160
Binding residue
(residue number reindexed from 1)		H26 H30 H31 Y34 H73 H160
Annotation score1
Enzymatic activity
Enzyme Commision number 1.15.1.1: superoxide dismutase.
Gene Ontology
Molecular Function
GO:0004784 superoxide dismutase activity
GO:0005506 iron ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0000303 response to superoxide
GO:0006801 superoxide metabolic process
GO:0019430 removal of superoxide radicals
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1isc, PDBe:1isc, PDBj:1isc
PDBsum1isc
PubMed7849024
UniProtP0AGD3|SODF_ECOLI Superoxide dismutase [Fe] (Gene Name=sodB)

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