Structure of PDB 1i5k Chain A Binding Site BS02

Receptor Information
>1i5k Chain A (length=79) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ECMHGSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNY
CRNPDRDLRPWCFTTDPNKRWEYCDIPRC
Ligand information
>1i5k Chain D (length=26) Species: 1314 (Streptococcus pyogenes) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
EKLTADAELQRLKNERHEEAELERLK
Receptor-Ligand Complex Structure
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PDB1i5k Structure and binding determinants of the recombinant kringle-2 domain of human plasminogen to an internal peptide from a group A Streptococcal surface protein.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
D26 Q28 A32 H33 I36 S38
Binding residue
(residue number reindexed from 1)
D27 Q29 A33 H34 I37 S39
Enzymatic activity
Enzyme Commision number 3.4.21.7: plasmin.
External links
PDB RCSB:1i5k, PDBe:1i5k, PDBj:1i5k
PDBsum1i5k
PubMed11350170
UniProtP00747|PLMN_HUMAN Plasminogen (Gene Name=PLG)

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