Structure of PDB 1h8p Chain A Binding Site BS02

Receptor Information
>1h8p Chain A (length=88) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EECVFPFVYRNRKHFDCTVHGSLFPWCSLDADYVGRWKYCAQRDYAKCVF
PFIYGGKKYETCTKIGSMWMSWCSLSPNYDKDRAWKYC
Ligand information
Ligand IDPC
InChIInChI=1S/C5H14NO4P/c1-6(2,3)4-5-10-11(7,8)9/h4-5H2,1-3H3,(H-,7,8,9)/p+1
InChIKeyYHHSONZFOIEMCP-UHFFFAOYSA-O
SMILES
SoftwareSMILES
ACDLabs 10.04O=P(O)(O)OCC[N+](C)(C)C
CACTVS 3.341C[N+](C)(C)CCO[P](O)(O)=O
OpenEye OEToolkits 1.5.0C[N+](C)(C)CCOP(=O)(O)O
FormulaC5 H15 N O4 P
NamePHOSPHOCHOLINE
ChEMBLCHEMBL1235161
DrugBankDB03945
ZINCZINC000001532692
PDB chain1h8p Chain A Residue 1111 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1h8p Sperm Coating Mechanism from the 1.8 A Crystal Structure of Pdc-109-Phosphorylcholine Complex
Resolution1.82 Å
Binding residue
(original residue number in PDB)		R31 H41
Binding residue
(residue number reindexed from 1)		R10 H20
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008201 heparin binding
Biological Process
GO:0007338 single fertilization
GO:0033700 phospholipid efflux
GO:0048240 sperm capacitation
GO:1902492 positive regulation of sperm capacitation
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0009986 cell surface

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1h8p, PDBe:1h8p, PDBj:1h8p
PDBsum1h8p
PubMed11937055
UniProtP02784|SFP1_BOVIN Seminal plasma protein PDC-109

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