Structure of PDB 1h76 Chain A Binding Site BS02

Receptor Information
>1h76 Chain A (length=677) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QKTVRWCTISNQEANKCSSFRENMSKAVKNGPLVSCVKKSSYLDCIKAIR
DKEADAVTLDAGLVFEAGLAPYNLKPVVAEFYGQKDNPQTHYYAVAVVKK
GSNFQWNQLQGKRSCHTGLGRSAGWIIPMGLLYDQLPEPRKPIEKAVASF
FSSSCVPCADPVNFPKLCQQCAGKGAEKCACSNHEPYFGYAGAFNCLKED
AGDVAFVKHSTVLENLPDKADRDQYELLCRDNTRRPVDDYENCYLAQVPS
HAVVARSVDGQEDSIWELLNQAQEHFGRDKSPDFQLFSSSHGKDLLFKDS
ANGFLKIPSKMDSSLYLGYQYVTALRNLREEECKKVRWCAIGHEETQKCD
AWSINSGGKIECVSAENTEDCIAKIVKGEADAMSLDGGYIYIAGKCGLVP
VLAENYKTEGENCVNTPEKGYLAVAVVKKSSGPDLNWNNLKGKKSCHTAV
DRTAGWNIPMGLLYNKINSCKFDQFFGEGCAPGSQRNSSLCALCIGSERA
PGRECLANNHERYYGYTGAFRCLVEKGDVAFVKDQVVQQNTDGKNKDDWA
KDLKQMDFELLCQNGAREPVDNAENCHLARAPNHAVVARDDKVTCVAEEL
LKQQAQFGRHVTDCSSSFCMFKSNTKDLLFRDDTQCLARVGKTTYESYLG
ADYITAVANLRKCSTSKLLEACTFHSA
Ligand information
Ligand IDCO3
InChIInChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
InChIKeyBVKZGUZCCUSVTD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(=O)([O-])[O-]
ACDLabs 10.04
CACTVS 3.341		[O-]C([O-])=O
FormulaC O3
NameCARBONATE ION
ChEMBL
DrugBankDB14531
ZINC
PDB chain1h76 Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1h76 The Crystal and Molecular Structures of Diferric Porcine and Rabbit Serum Transferrins at Resolutions of 2.15 And 2.60A, Respectively
Resolution2.15 Å
Binding residue
(original residue number in PDB)		D396 T458 R462 A464 Y526 H594
Binding residue
(residue number reindexed from 1)		D386 T448 R452 A454 Y516 H584
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008199 ferric iron binding
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis
GO:0019731 antibacterial humoral response
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0055037 recycling endosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1h76, PDBe:1h76, PDBj:1h76
PDBsum1h76
PubMed11752780
UniProtP09571|TRFE_PIG Serotransferrin (Gene Name=TF)

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