Structure of PDB 1gwn Chain A Binding Site BS02

Receptor Information
>1gwn Chain A (length=179) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRI
ELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEI
QEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGA
ATYIECSALQSENSVRDIFHVATLACVNK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain1gwn Chain A Residue 1202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1gwn Crystal Structure of the Core Domain of Rhoe/Rnd3: A Constitutively Activated Small G Protein
Resolution2.1 Å
Binding residue
(original residue number in PDB)		T37 T55
Binding residue
(residue number reindexed from 1)		T16 T34
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007264 small GTPase-mediated signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:1gwn, PDBe:1gwn, PDBj:1gwn
PDBsum1gwn
PubMed12009891
UniProtP61588|RND3_MOUSE Rho-related GTP-binding protein RhoE (Gene Name=Rnd3)

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