Structure of PDB 1gqb Chain A Binding Site BS02

Receptor Information
>1gqb Chain A (length=131) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HDDCQVTNPSTGHLFDLSSLSGRAGFTAAYSEKGLVYMSICGENENCPPG
VGACFGQTRISVGKANKRLRYVDQVLQLVYKDGSPCPSKSGLSYKSVISF
VCRPENRPMLISLDKQTCTLFFSWHTPLACE
Ligand information
Ligand IDBR
InChIInChI=1S/BrH/h1H/p-1
InChIKeyCPELXLSAUQHCOX-UHFFFAOYSA-M
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Br-]
FormulaBr
NameBROMIDE ION
ChEMBL
DrugBank
ZINC
PDB chain1gqb Chain A Residue 1144 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1gqb Locating the Anomalous Scatterer Substructures in Halide and Sulfur Phasing
Resolution1.8 Å
Binding residue
(original residue number in PDB)		D87 K100
Binding residue
(residue number reindexed from 1)		D82 K95
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005537 D-mannose binding
GO:0038023 signaling receptor activity
Biological Process
GO:0007041 lysosomal transport

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Molecular Function
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Biological Process
External links
PDB RCSB:1gqb, PDBe:1gqb, PDBj:1gqb
PDBsum1gqb
PubMed12499540
UniProtP11717|MPRI_HUMAN Cation-independent mannose-6-phosphate receptor (Gene Name=IGF2R)

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