Structure of PDB 1ge7 Chain A Binding Site BS02

Receptor Information
>1ge7 Chain A (length=167) Species: 5627 (Grifola frondosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TYNGCSSSEQSALAAAASAAQSYVAESLSYLQTHTAATPRYTTWFGSYIS
SRHSTVLQHYTDMNSNDFSSYSFDCTCTAAGTFAYVYPNRFGTVYLCGAF
WKAPTTGTDSQAGTLVHESSHFTRNGGTKDYAYGQAAAKSLATMDPDKAV
MNADNHEYFSENNPAQS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1ge7 Chain A Residue 200 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1ge7 Structure of a new 'aspzincin' metalloendopeptidase from Grifola frondosa: implications for the catalytic mechanism and substrate specificity based on several different crystal forms.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		H117 H121 D130
Binding residue
(residue number reindexed from 1)		H117 H121 D130
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) H117 E118 H121 D130 Y133
Catalytic site (residue number reindexed from 1) H117 E118 H121 D130 Y133
Enzyme Commision number 3.4.24.20: peptidyl-Lys metalloendopeptidase.
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity

View graph for
Molecular Function
External links
PDB RCSB:1ge7, PDBe:1ge7, PDBj:1ge7
PDBsum1ge7
PubMed11223512
UniProtP81054|PLMP_GRIFR Peptidyl-Lys metalloendopeptidase (Gene Name=MEP)

[Back to BioLiP]