Structure of PDB 1fno Chain A Binding Site BS02

Receptor Information
>1fno Chain A (length=408) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDKLLERFLHYVSLDTQSKSGVRQVPSTEGQWKLLRLLKQQLEEMGLVNI
TLSEKGTLMATLPANVEGDIPAIGFISHVDTSPDFSGKNVNPQIVENYRG
GDIALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGVAEIMT
ALAVLKGNPIPHGDIKVAFTPDEEVGKGAKHFDVEAFGAQWAYTVDGGGV
GELEFENFNAASVNIKIVGNNVHPGTAKGVMVNALSLAARIHAEVPADEA
PETTEGYEGFYHLASMKGTVDRAEMHYIIRDFDRKQFEARKRKMMEIAKK
VGKGLHPDCYIELVIEDSYYNMREKVVEHPHILDIAQQAMRDCHITPEMK
PIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEKAVQVIVRI
AELTAKRG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1fno Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1fno Structure of Peptidase T from Salmonella typhimurium
Resolution2.4 Å
Binding residue
(original residue number in PDB)		D140 E174 H379
Binding residue
(residue number reindexed from 1)		D140 E174 H379
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.11.4: tripeptide aminopeptidase.
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0045148 tripeptide aminopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0006518 peptide metabolic process
GO:0043171 peptide catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1fno, PDBe:1fno, PDBj:1fno
PDBsum1fno
PubMed11856302
UniProtP26311|PEPT_SALTY Peptidase T (Gene Name=pepT)

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