Structure of PDB 1ff1 Chain A Binding Site BS02

Receptor Information
>1ff1 Chain A (length=95) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PWAVKPEDKAKYDAIFDSLSPVNGFLSGDKVKPVLLNSKLPVDILGRVWE
LSDIDHDGMLDRDEFAVAMFLVYCALEKEPVPMSLPPALVPPSKR
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1ff1 Chain A Residue 113 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1ff1 Molecular mechanism of NPF recognition by EH domains.
ResolutionN/A
Binding residue
(original residue number in PDB)		D58 D60 D62 M64 E69
Binding residue
(residue number reindexed from 1)		D53 D55 D57 M59 E64
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:1ff1, PDBe:1ff1, PDBj:1ff1
PDBsum1ff1
PubMed11062555
UniProtP42566|EPS15_HUMAN Epidermal growth factor receptor substrate 15 (Gene Name=EPS15)

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