Structure of PDB 1f5f Chain A Binding Site BS02

Receptor Information
>1f5f Chain A (length=172) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPAVHLSNGPGQEPIAVMTFDLTKITKTSSSFEVRTWDPEGVIFYGDTNP
KDDWFMLGLRDGRPEIQLHNHWAQLTVGAGPRLDDGRWHQVEVKMEGDSV
LLEVDGEEVLRLRQVSGPLHPIMRIALGGLLFPASNLRLPLVPALDGCLR
RDSWLDKQAEISASAPTSLRSC
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1f5f Chain A Residue 251 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1f5f Steroid-binding specificity of human sex hormone-binding globulin is influenced by occupancy of a zinc-binding site.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		D65 H83 H136
Binding residue
(residue number reindexed from 1)		D53 H71 H120
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1f5f, PDBe:1f5f, PDBj:1f5f
PDBsum1f5f
PubMed10859323
UniProtP04278|SHBG_HUMAN Sex hormone-binding globulin (Gene Name=SHBG)

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