Structure of PDB 1exi Chain A Binding Site BS02

Receptor Information
>1exi Chain A (length=275) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ESYYSIGEVSKLANVSIKALRYYDKIDLFKPAYVDPDTSYRYYTDSQLIH
LDLIKSLKYIGTPLEEMKKAQDLEMEELFAFYTEQERQIREKLDFLSALE
QTISLVKKRMKRQMEYPALGEVFVLDEEEIRIIQTEAEGIGPENVLNASY
SKLKKFIESADGFTNNSYGATFSFQPYTSIDEMTYRHIFTPVLTNKQISS
ITPDMEITTIPKGRYACIAYNFSPEHYFLNLQKLIKYIADRQLTVVSDVY
ELIIPIHYSPKKQEEYRVEMKIRIA
Ligand information
Ligand ID118
InChIInChI=1S/4C6H5.Sb/c4*1-2-4-6-5-3-1;/h4*1-5H;/q;;;;+1
InChIKeySZOUUWBVOLRGQM-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04c1c(cccc1)[Sb+](c2ccccc2)(c3ccccc3)c4ccccc4
CACTVS 3.341
OpenEye OEToolkits 1.5.0		c1ccc(cc1)[Sb+](c2ccccc2)(c3ccccc3)c4ccccc4
FormulaC24 H20 Sb
NameTETRAPHENYLANTIMONIUM ION
ChEMBL
DrugBank
ZINC
PDB chain1exi Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1exi Crystal structure of the transcription activator BmrR bound to DNA and a drug.
Resolution3.12 Å
Binding residue
(original residue number in PDB)		P144 E145 V147 L148 N149 F224 Y268
Binding residue
(residue number reindexed from 1)		P142 E143 V145 L146 N147 F222 Y266
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1exi, PDBe:1exi, PDBj:1exi
PDBsum1exi
PubMed11201751
UniProtP39075|BMRR_BACSU Multidrug-efflux transporter 1 regulator (Gene Name=bmrR)

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