Structure of PDB 1evw Chain A Binding Site BS02

Receptor Information
>1evw Chain A (length=162) Species: 5791 (Physarum polycephalum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALTNAQILAVIDSWEETVGQFPVITHHVPLGGGLQGTLHCYEIPLAAPYG
VGFAKNGPTRWQYKRTINQVVHRWGSHTVPFLLEPDNINGKTCTASHLCH
NTRCHNPLHLCWESADDNKGRNWCPGPNGGCVHAVVCLRQGPLYGPGATV
AGPQQRGSHFVV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1evw Conformational changes and cleavage by the homing endonuclease I-PpoI: a critical role for a leucine residue in the active site.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R61 Q63 R74 T79 T95 A96 H98 N119
Binding residue
(residue number reindexed from 1)		R60 Q62 R73 T78 T94 A95 H97 N118
Binding affinityPDBbind-CN: Kd=10pM
Enzymatic activity
Catalytic site (original residue number in PDB) N119
Catalytic site (residue number reindexed from 1) N118
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
Biological Process
GO:0006314 intron homing

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Molecular Function
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Biological Process
External links
PDB RCSB:1evw, PDBe:1evw, PDBj:1evw
PDBsum1evw
PubMed10891275
UniProtQ94702|PPO1_PHYPO Intron-encoded endonuclease I-PpoI

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