Structure of PDB 1e12 Chain A Binding Site BS02

Receptor Information
>1e12 Chain A (length=239) Species: 2242 (Halobacterium salinarum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RENALLSSSLWVNVALAGIAILVFVYMGRTIRPGRPRLIWGATLMIPLVS
ISSYLGLLSGLTVGMIEMPAGHALAGEMVRSQWGRYLTWALSTPMILLAL
GLLADVDLGSLFTVIAADIGMCVTGLAAAMTTSALLFRWAFYAISCAFFV
VVLSALVTDWAASASSAGTAEIFDTLRVLTVVLWLGYPIVWAVGVEGLAL
VQSVGATSWAYSVLDVFAKYVFAFILLRWVANNERTVAV
Ligand information
Ligand IDPLM
InChIInChI=1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18)
InChIKeyIPCSVZSSVZVIGE-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0CCCCCCCCCCCCCCCC(=O)O
ACDLabs 10.04O=C(O)CCCCCCCCCCCCCCC
CACTVS 3.341CCCCCCCCCCCCCCCC(O)=O
FormulaC16 H32 O2
NamePALMITIC ACID
ChEMBLCHEMBL82293
DrugBankDB03796
ZINCZINC000006072466
PDB chain1e12 Chain A Residue 700 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1e12 Structure of Light-Driven Chloride Pump Halorhodopsin at 1.8 A Resolution
Resolution1.8 Å
Binding residue
(original residue number in PDB)		F135 V146
Binding residue
(residue number reindexed from 1)		F112 V123
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0009881 photoreceptor activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0007602 phototransduction
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1e12, PDBe:1e12, PDBj:1e12
PDBsum1e12
PubMed10827943
UniProtP0DMH7|BACH_HALSA Halorhodopsin (Gene Name=hop)

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