Structure of PDB 1e0x Chain A Binding Site BS02

Receptor Information

>1e0x Chain A (length=309) Species: 1916 (Streptomyces lividans)

AESTLGAAAAQSGRYFGTAIASGRLSDSTYTSIAGREFNMVTAENEMKID
ATEPQRGQFNFSSADRVYNWAVQNGKQVRGHTLAWHSQQPGWMQSLSGSA
LRQAMIDHINGVMAHYKGKIVQWDVVNEAFADGSSGARRDSNLQRSGNDW
IEVAFRTARAADPSAKLCYNDYNVENWTWAKTQAMYNMVRDFKQRGVPID
CVGFQSHFNSGSPYNSNFRTTLQNFAALGVDVAITELDIQGAPASTYANV
TNDCLAVSRCLGITVWGVRDSDSWRSEQTPLLFNNDGSKKAAYTAVLDAL
NGGDSSEPP

Ligand information

• Ligand ID: XYP
• InChI: InChI=1S/C5H10O5/c6-2-1-10-5(9)4(8)3(2)7/h2-9H,1H2/t2-,3+,4-,5-/m1/s1
• InChIKey: SRBFZHDQGSBBOR-KKQCNMDGSA-N
• SMILES:
  OpenEye OEToolkits 1.5.0: C1C(C(C(C(O1)O)O)O)O
  CACTVS 3.341: O[C@@H]1CO[C@@H](O)[C@H](O)[C@H]1O
  OpenEye OEToolkits 1.5.0: C1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O
  CACTVS 3.341: O[CH]1CO[CH](O)[CH](O)[CH]1O
  ACDLabs 10.04: OC1C(O)COC(O)C1O
• Formula: C5 H10 O5
• Name: beta-D-xylopyranose;
  beta-D-xylose;
  D-xylose;
  xylose
• ZINC: ZINC000001529215
• PDB chain: 1e0x Chain C Residue 2

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1e0x Substrate Specificity in Glycoside Hydrolase Family 10. Structural and Kinetic Analysis of the Streptomyces Lividans Xylanase 10A
• Resolution: 1.65 Å
• Binding residue (original residue number in PDB): E44 N45 K48 Q88 W266 W274
• Binding residue (residue number reindexed from 1): E44 N45 K48 Q88 W266 W274
• Annotation score: 4

Enzymatic activity

• Catalytic site (original residue number in PDB): E128 N170 H207 E236 D238
• Catalytic site (residue number reindexed from 1): E128 N170 H207 E236 D238
• Enzyme Commision number: 3.2.1.8: endo-1,4-beta-xylanase.

Gene Ontology

Molecular Function

• GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds

Biological Process

• GO:0005975 carbohydrate metabolic process

External links

• PDB: RCSB:1e0x, PDBe:1e0x, PDBj:1e0x
• PDBsum: 1e0x
• PubMed: 10930426
• UniProt: P26514|XYNA_STRLI Endo-1,4-beta-xylanase A (Gene Name=xlnA)