Structure of PDB 1dot Chain A Binding Site BS02

Receptor Information
>1dot Chain A (length=686) Species: 8839 (Anas platyrhynchos) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APPKTTVRWCTISSAEEKKCNSLKDHMQQERVTLSCVQKATYLDCIKAIS
NNEADAISLDGGQVFEAGLAPYKLKPIAAEVYERSGGSTTSYYAVAVVKK
GTDFMIKDLRGKTSCHTGLGRSAGWNIPIGTLIHREDIEWEGIESGISEQ
AVAKFFSASCVPGATIEQKLCRQCKGDAKTKCLRNGPYSGYSGAFQCLKD
GKGDVAFVKHTTVQENAPEEKDEYELLCLDGSRQPVDSYKTCNWARVAAH
AVVARDDSKIDDIWSFLGMQAYSLGVDTTSDFHLFGPPGKKDPVLKDLLF
KDSAIMLKRVPELMDSQLYLGFEYYSAIQSLRKDQLTVGPRENKIQWCAV
GKDEKSKCDRWSVVSNGEVECTILDDNKDCIVKITKGEADAISLDGGFVY
TAGVCGLVPVVGESYEDETQCSKDEEQPAYYFAVAVVKKSSAITWNNLQG
KKSCHTAVGRTAGWNIPMGLIHNKTGSCDFDDYFSEGCAPGSPPNSRLCK
LCQGSGENLLEKCVASSHEKYYGYTGALRCLVEQGDVAFIKHSTVGENVS
GSNKDDWAKGLTRDDFELLCTNGKRAKTMDYKTCHLAKVPTHAVVARPEK
ANKIRELLEGQEKLFGLHGTEKERFMMFQSQTKDLLFKALTKCLVKLRQG
ITYKEFLGDEYYASVASLNTCNPSDLLQVCTFLEDK
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain1dot Chain A Residue 688 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1dot Structure of diferric duck ovotransferrin at 2.35 A resolution.
Resolution2.35 Å
Binding residue
(original residue number in PDB)		D395 Y431 Y524 H592
Binding residue
(residue number reindexed from 1)		D395 Y431 Y524 H592
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0019731 antibacterial humoral response
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0055037 recycling endosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1dot, PDBe:1dot, PDBj:1dot
PDBsum1dot
PubMed15299626
UniProtP56410|TRFE_ANAPL Ovotransferrin

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