Structure of PDB 1c3n Chain A Binding Site BS02

Receptor Information
>1c3n Chain A (length=144) Species: 4233 (Helianthus tuberosus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDIAVQAGPWGGNGGKRWLQTAHGGKITSIIIKGGTCIFSIQFVYKDKDN
IEYHSGKFGVLGDKAETITFAEDEDITAISGTFGAYYHMTVVTSLTFQTN
KKVYGPFGTVASSSFSLPLTKGKFAGFFGNSGDVLDSIGGVVVP
Ligand information
Ligand IDMAN
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-PQMKYFCFSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@@H](O)[C@@H](O)[C@@H]1O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@@H]([C@H](O1)O)O)O)O)O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-mannopyranose;
alpha-D-mannose;
D-mannose;
mannose
ChEMBLCHEMBL365590
DrugBank
ZINCZINC000003860903
PDB chain1c3n Chain B Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1c3n Helianthus tuberosus lectin reveals a widespread scaffold for mannose-binding lectins.
Resolution2.45 Å
Binding residue
(original residue number in PDB)		G17 G18 G135 D136 V137 D139
Binding residue
(residue number reindexed from 1)		G14 G15 G132 D133 V134 D136
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:1c3n, PDBe:1c3n, PDBj:1c3n
PDBsum1c3n
PubMed10647178
UniProtQ9ZQY5

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