Structure of PDB 1c1m Chain A Binding Site BS02
Receptor Information
>1c1m Chain A (length=240) Species:
9823
(Sus scrofa) [
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VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRE
LTFRVVVGEHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLA
QSVTLNSYVQLGVLPRAGTILANNSPCYITGWGLTRTNGQLAQTLQQAYL
PTVDYAICSSSSYWGSTVKNSMVCAGGDGVRSGCQGDSGGPLHCLVNGQY
AVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVIASN
Ligand information
Ligand ID
XE
InChI
InChI=1S/Xe
InChIKey
FHNFHKCVQCLJFQ-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0
[Xe]
Formula
Xe
Name
XENON
ChEMBL
CHEMBL1236802
DrugBank
DB13453
ZINC
PDB chain
1c1m Chain A Residue 260 [
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Receptor-Ligand Complex Structure
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PDB
1c1m
Exploring hydrophobic sites in proteins with xenon or krypton.
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
C191 F215 V216
Binding residue
(residue number reindexed from 1)
C184 F208 V209
Annotation score
1
Enzymatic activity
Catalytic site (original residue number in PDB)
H57 D102 Q192 G193 D194 S195 G196
Catalytic site (residue number reindexed from 1)
H45 D93 Q185 G186 D187 S188 G189
Enzyme Commision number
3.4.21.36
: pancreatic elastase.
Gene Ontology
Molecular Function
GO:0004252
serine-type endopeptidase activity
GO:0005515
protein binding
GO:0008236
serine-type peptidase activity
GO:0046872
metal ion binding
Biological Process
GO:0006508
proteolysis
Cellular Component
GO:0005576
extracellular region
GO:0005615
extracellular space
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Cellular Component
External links
PDB
RCSB:1c1m
,
PDBe:1c1m
,
PDBj:1c1m
PDBsum
1c1m
PubMed
9443341
UniProt
P00772
|CELA1_PIG Chymotrypsin-like elastase family member 1 (Gene Name=CELA1)
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