Structure of PDB 1bzo Chain A Binding Site BS02

Receptor Information

>1bzo Chain A (length=151) Species: 658 (Photobacterium leiognathi subsp. leiognathi)

QDLTVKMTDLQTGKPVGTIELSQNKYGVVFIPELADLTPGMHGFHIHQNG
SCASSEKDGKVVLGGAAGGHYDPEHTNKHGFPWTDDNHKGDLPALFVSAN
GLATNPVLAPRLTLKELKGHAIMIHAGGDNHSDMPKALGGGGARVACGVI
Q

Ligand information

• Ligand ID: CU
• InChI: InChI=1S/Cu/q+2
• InChIKey: JPVYNHNXODAKFH-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Cu+2]
  CACTVS 3.341: [Cu++]
• Formula: Cu
• Name: COPPER (II) ION
• DrugBank: DB14552
• PDB chain: 1bzo Chain A Residue 152

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1bzo Evolutionary constraints for dimer formation in prokaryotic Cu,Zn superoxide dismutase.
• Resolution: 2.1 Å
• Binding residue (original residue number in PDB): H44 H46 H61 H118
• Binding residue (residue number reindexed from 1): H45 H47 H70 H125
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 1.15.1.1: superoxide dismutase.

Gene Ontology

Molecular Function

• GO:0004784 superoxide dismutase activity
• GO:0005507 copper ion binding
• GO:0016209 antioxidant activity
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006801 superoxide metabolic process
• GO:0019430 removal of superoxide radicals
• GO:0098869 cellular oxidant detoxification

Cellular Component

• GO:0042597 periplasmic space

External links

• PDB: RCSB:1bzo, PDBe:1bzo, PDBj:1bzo
• PDBsum: 1bzo
• PubMed: 9878406
• UniProt: P00446|SODC_PHOLE Superoxide dismutase [Cu-Zn] (Gene Name=sodC)