Structure of PDB 1bgb Chain A Binding Site BS02

Receptor Information
>1bgb Chain A (length=237) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLRSDLINALYDENQKYDVCGIISAEGKIYPLGSDTKVLSTIFELFSRPI
INKIAEKHGYIVEEPKQQNHYPDFTLYKPSEPNKKIAIDIKTTYTNKENE
KIKFTLGGYTSFIRNNTKNIVYPFDQYIAHWIIGYVYTRVKTYNINELNE
IPKPYKGVKVFLQDKWVIAGDLAGSGNTTNIGSIHAHYKDFVEGKGIFDS
EDEFLDYWRNYERTSQLRNDKYNNISEYRNWIYRGRK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1bgb Recognition of flanking DNA sequences by EcoRV endonuclease involves alternative patterns of water-mediated contacts.
Resolution2.0 Å
Binding residue
(original residue number in PDB)
T37 N70 K92 T93 T94 T106 T111 S112 K119 S183 T186 N188
Binding residue
(residue number reindexed from 1)
T36 N69 K91 T92 T93 T105 T110 S111 K118 S175 T178 N180
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function

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Biological Process
External links
PDB RCSB:1bgb, PDBe:1bgb, PDBj:1bgb
PDBsum1bgb
PubMed9705308
UniProtP04390|T2E5_ECOLX Type II restriction enzyme EcoRV (Gene Name=ecoRVR)

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