Structure of PDB 1anv Chain A Binding Site BS02

Receptor Information
>1anv Chain A (length=314) Species: 28285 (Human adenovirus 5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SAWEKGMEAARALMDKYHVDNDLKANFKLLPDQVEALAAVCKTWLNEEHR
GLQLTFTSNKTFVTMMGRFLQAYLQSFAEVTYKHHEPTGCALWLHRCAEI
EGELKCLHGSIMINKEHVIENVVQISNTDARCCVHDAACPANQFSGKSCG
MFFSEGAKAQVAFKQIKAFMQALYPNAQTGHGHLLMPLRCECNSKPGHAP
FLGRQLPKLTPFALSNAEDLDADLISDKSVLASVHHPALIVFQCCNPGGP
NCDFKISAPDLLNALVMVRSLWSENFTELPRMVVPEFKWSTKHQYRNVSL
PVAHSDARQNPFDF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1anv Chain A Residue 531 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1anv Conformational change of the adenovirus DNA-binding protein induced by soaking crystals with K3UO2F5 solutions.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		C396 C398 C450 C467
Binding residue
(residue number reindexed from 1)		C190 C192 C244 C252
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008270 zinc ion binding
Biological Process
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006351 DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1anv, PDBe:1anv, PDBj:1anv
PDBsum1anv
PubMed15299602
UniProtP03265|DNB2_ADE05 DNA-binding protein (Gene Name=DBP)

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