Structure of PDB 1ala Chain A Binding Site BS02

Receptor Information
>1ala Chain A (length=316) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KYTRGTVTAFSPFDARADAEALRKAMKGMGTDEETILKILTSRNNAQRQE
IASAFKTLFGRDLVDDLKSELTGKFETLMVSLMRPARIFDAHALKHAIKG
AGTNEKVLTEILASRTPAEVQNIKQVYMQEYEANLEDKITGETSGHFQRL
LVVLLQANRDPDGRVEEALVEKDAQVLFRAGELKWGTDEETFITILGTRS
VSHLRRVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCIRSVPAYFA
ETLYYSMKGAGTDDDTLIRVMVSRSEIDLLDIRHEFRKNFAKSLYQMIQK
DTSGDYRKALLLLCGG
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1ala Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1ala Structure of chicken annexin V at 2.25-A resolution.
Resolution2.25 Å
Binding residue
(original residue number in PDB)		I100 K101 G102 G104 E144
Binding residue
(residue number reindexed from 1)		I98 K99 G100 G102 E142
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001786 phosphatidylserine binding
GO:0005262 calcium channel activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005544 calcium-dependent phospholipid binding
Biological Process
GO:0050819 negative regulation of coagulation
GO:0055074 calcium ion homeostasis
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0012506 vesicle membrane
GO:0031982 vesicle
GO:0034704 calcium channel complex
GO:0042383 sarcolemma

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1ala, PDBe:1ala, PDBj:1ala
PDBsum1ala
PubMed8471604
UniProtP17153|ANXA5_CHICK Annexin A5 (Gene Name=ANXA5)

[Back to BioLiP]