Structure of PDB 1aj4 Chain A Binding Site BS02

Receptor Information
>1aj4 Chain A (length=160) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ADIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQN
PTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMKDDSKGKTEEELSDLF
RMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYD
EFLEFMKGVE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1aj4 Chain A Residue 163 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1aj4 Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain.
ResolutionN/A
Binding residue
(original residue number in PDB)		D105 N107 D109 Y111 I112 E116
Binding residue
(residue number reindexed from 1)		D104 N106 D108 Y110 I111 E115
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0031013 troponin I binding
GO:0046872 metal ion binding
GO:0048306 calcium-dependent protein binding
Biological Process
GO:0003009 skeletal muscle contraction
GO:0060048 cardiac muscle contraction
Cellular Component
GO:1990584 cardiac Troponin complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1aj4, PDBe:1aj4, PDBj:1aj4
PDBsum1aj4
PubMed9218458
UniProtP09860|TNNC1_CHICK Troponin C, slow skeletal and cardiac muscles (Gene Name=TNNC1)

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