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Receptor Information

>8buu Chain 9 (length=573) Species: 220686 (Neobacillus vireti) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KNQRTIVKVSGLEKSFHLRKVLQNLHFEIKNGDRIGLVGYNGTGKTTLAN
IIFGKITPDNGLIEKSRDLRMGYLSQSIDYEVSHFQQSIAEVEEHELFQH
ASSLGLNKVFDWSEDRLTHLSGGEKLKLALSMVWATKPDFLILDQPTNHL
DFTGINWLVSELEKFHGPVLIISHDRHFLDKTVNRIFELEESRIQFFNGN
YSDYRIEKEQRIANQRHQYQVQQRQIEKIETQMVQLKSWSEKAHRDSTKQ
GSASERRQIGFKEYHRVKAKKLDNQVKSKMKRLQNELNKHKLEKPNEEAA
VRFQFDSHGKRGKRIIEAKKLTKMFDDRILFQDSPFYINHGDRIGLLGEN
GCGKTTLIKMILGDDLSFVGELWKSDSVKIAYLSQDVADLSADKTAIEAL
GFTDRESILKARTLLANLGLKEQLITKPIGTLSLGERTRVKLVDMLMKEY
DVLILDQPTNHLDLPSREQLEQTLSEFTGTIITVSHDHYFLNKLCDRLLV
FENQQIKRFEMKPQEYLNKDVKSGDRSEEAMLIIENKIALILGELSLIDQ
NNPKYYRLDEEFNELLKQKRNLK

>8buu Chain V (length=73) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gcgggguggagcaguucgguagcucgucgggcucauaacccgaaggucgc
agguucaaauccugcccccgcaa

<<<<<<..<<<<.........>>>>.<<<<<.......>>>>>.....<<
<<<.......>>>>>>>>>>>..

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8buu Genome-encoded ABCF factors implicated in intrinsic antibiotic resistance in Gram-positive bacteria: VmlR2, Ard1 and CplR.
Resolution	2.9 Å
Binding residue (original residue number in PDB)	R247 R304 L411 R414 T415 A418 N419 K423
Binding residue (residue number reindexed from 1)	R245 R302 L409 R412 T413 A416 N417 K421

Enzyme Commision number

	Molecular Function
GO:0005524	ATP binding
GO:0016887	ATP hydrolysis activity

PDB	RCSB:8buu, PDBe:8buu, PDBj:8buu
PDBsum	8buu
PubMed	36951104
UniProt	W1SM44

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Structure of PDB 8buu Chain 9 Binding Site BS02