Structure of PDB 7pis Chain 9 Binding Site BS02

Receptor Information
>7pis Chain 9 (length=682) Species: 272634 (Mycoplasmoides pneumoniae M129) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TVDLINFRNFGIMAHIDAGKTTTSERILFHSGRIHKIGETHDGESVMDWM
EQEKERGITITSAATSVSWKNCSLNLIDTPGHVDFTVEVERSLRVLDGAI
AVLDAQMGVEPQTETVWRQASRYEVPRIIFVNKMDKTGANFERSVQSIQQ
RLGVKAVPIQLPIGAENDFNGIIDLIEEKVYFFDGGKEEKAEEKPIPDQF
KDQVKQMRAHLVEEVANFDDQLMADYLEGKEISIADIKRCIRKGVIGCQF
FPVLCGSAFKNKGIKLLLDAVVDFLPSPVDVPQAKAYGEDGNEVLISASD
DAPFVGLAFKVATDPFVGRLTFVRVYSGVLKSGSYVKNVRKNKKERVSRL
VKMHAQNRNEIEEIRAGDICAIIGLKDTTTGETLVDDKIDVQLEAMQFAQ
PVISLAVEPKTKADQEKMSIALSKLAEEDPTFKTFTDPETGQTIIAGMGE
LHLDILVDRMRREFKVEVNVGAPQVSFRETFNKESEVEGKYIKQSGGRGQ
YGHVKIRFEPNKDKGFEFVDKIVGGRIPREYIKPVQAGLENAMASGPLAG
YPMIDIKATLFDGSFHEVDSSEMAFKIAASLALKEAGKVCSPVLLEPIMA
IEVTVPEQYFGDTMGDISSRRGLIEGTEQRDNVQVIKAKVPLKEMFGYAT
DLRSFSQGRGNYVMQFSHYAETPKSVVNEIIA
Ligand information
>7pis Chain 5 (length=1493) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ucugagaguuugauccuggcucaggauuaacgcuggcggcaugccuaaua
caugcaagucgaucgaaaguaguaauacuuuagaggcgaacgggugagua
acacguauccaaucuaccuuauaaugggggauaacuaguugaaagacuag
cuaauaccgcauaagaacuuugguucgaaucaaaguugaaaggaccugca
aggguucguuauuugaugagggugcgccauaucagcuaguugguggggua
acggccuaccaaggcaaugacguguagcuaugcugagaaguagaauagcc
acaaugggacugagacacggcccauacuccuacgggaggcagcaguaggg
aauuuuucacaaugagcgaaagcuugauggagcaaugccgcgugaacgau
gaaggucuuuaagauuguaaaguucuuuuauuugggaagaaugacuuuag
cagguaauggcuagaguuugacuguaccauuuugaauaagugacgacuaa
cuaugugccagcagucgcgguaauacauaggucgcaagcguuauccggau
uuauugggcguaaagcaagcgcaggcggauugaaaagucugguguuaaag
gcagcugcuuaacaguuguaugcauuggaaacuauuaaucuagagugugg
uagggaguuuuggaauuucauguggagcggugaaaugcguagauauauga
aggaacaccaguggcgaaggcgaaaacuuaggccauuacugacgcuuagg
cuugaaaguguggggagcaaauaggauuagauacccuaguaguccacacc
guaaacgauagauacuagcugucggggcgauccccucgguagugaaguua
acacauuaaguaucucgccuggguaguacauucgcaagaaugaaacucaa
acggaauugacggggacccgcacaagugguggagcauguugcuuaauucg
acgguacacgaaaaaccuuaccuagacuugacauccuuggcaaaguuaug
gaaacauaaugccgagugacagguggugcaugguugucgucagcucgugu
cgugagauguuggguuaagucccgcaacgagcgcaacccuuaucguuagu
uacauugucuagcgagacugcuaaugcaaauuggaggaaggaagggauga
cgucaaaucaucaugccccuuaugucuagggcugcaaacgugcuacaaug
gccaauacaaacagucgccagcuuguaaaagugagcaaaucuguaaaguu
ggucucaguucggauugagggcugcaauucguccucaugaagucggaauc
acuaguaaucgcgaaucagcuaugucgcggugaauacguucucgggucuu
guacacaccgcccgucaaacuaugaaagcugguaauauuuaaaaacgugu
ugcuaaccauuaggaagcgcaugucaaggauagcaccggugauuggaguu
aagucguaacaagguaccccuacgagaacguggggguggauca
.....<<<<....(((.>.>>>.<<...<<<<<...<<<<.<......<<
<.<<<..<<<..<<.<<<<<<....>>>>>>.>>>>>......<<.....
...<<<.<<<..<<...<.......<.<<.....<<<<<......>>>>>
......>>.>.....<<<<<<<........>>>>>>>....<<<<<<...
.>>>>>>.......>..>>>>>.>>>.<<.....<<<....<<<<<<...
....>>>>>>..>>>.......>>..<<<<<<<<....>>>...>>>>>.
>>.<<<<<.<.........>>>>>>.<.<<....>>.>...>>>>>>...
......<<<....<<<<....>>>>..>>>...>..>>>>...<<<<...
.....<<.....>>.......>>>>.......<<<.......<<<<<<<<
<........>>>>>>>>>........>>>..........<<<<<(((...
<<<<<.....<<.)))>>.......>>>>>>>>>>..>>>>>.>.>....
......<<<((.....<<<<...<<<.<<<<<<..<<<<<.<<<<.....
<<<<<<<.....>>>>>>>..>>>>.>>>..>>.>>>>>>....<<<<<<
....<<<<<<<....<<<<<<<<...<<<......>>>......>>>>>>
>>...........<<....>>.>>>>>>>...>>>>.>>....>>>...>
>>>....<<<<<<...<<...<<<<.........>>>>...>>>>>>>>.
.........<<<<<<..<<<<<<<<<<......>>>>>>>>>>...<<..
))>>.....>>>>>>.>>>.<<........<<<....>>>......>>..
..)))..<<<<..<<<<<<<.....<......<<<<<<<<<.......<<
........>>..........<<<<<<<......<...<.......<<<<<
....>>>>>....>...>....<.<<<..<<<<<<.......<<<<<<<<
<....>>>..<<<<......>>>>..>>>>>>.....<<<..<<<<<<<.
........>>>>>>>.....<<<<<....>>>>>.........>>>....
.....>>>...>>>>>>>.....>>>>>>>....>.>>>>>>>>.....<
<<<<<<.....<<<..<<..<<<<....>>>>..>>....>>>....>>>
>>>>...........<<<<<<<........>>>>>>>.............
.>.....<<<<<<<..........>>>>>>>...........>>>>>>>.
>>.>>....<..<<.<.<<<<...<..<<<<<<..<..<<....<<<<<.
<<<<..<<....>>.>>>>>>>>>...>>..>..>>>>>>..>...>>>>
..>.>>...>.....<<<<<<<<<....>>>>>>>>>......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7pis Visualizing translation dynamics at atomic detail inside a bacterial cell.
Resolution15.0 Å
Binding residue
(original residue number in PDB)		H38 K39 I40 G41 H44 D45 P318 F319 V320 R349 S351 R352 R361 E363 Y494 K496 Q497 S498 G499 G500 R501 Q503 Y504 R529 H569 E570 V571 D572 S573 M576
Binding residue
(residue number reindexed from 1)		H35 K36 I37 G38 H41 D42 P315 F316 V317 R346 S348 R349 R358 E360 Y491 K493 Q494 S495 G496 G497 R498 Q500 Y501 R526 H566 E567 V568 D569 S570 M573
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
GO:0032790 ribosome disassembly
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7pis, PDBe:7pis, PDBj:7pis
PDBsum7pis
PubMed36171285
UniProtP75544|EFG_MYCPN Elongation factor G (Gene Name=fusA)

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