Structure of PDB 8p16 Chain 6 Binding Site BS02

Receptor Information
>8p16 Chain 6 (length=361) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
INPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERA
QALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAEL
DALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYL
RWAESRGFKTEIIKESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVR
KSPFDSGGRRHTSFSSAFVYPEVDDDIDIEINPADLRIDVYRTSGAGGQH
VNRTESAVRITHIPTGIVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKK
NAEKQAMEDNKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGSL
DQFIEASLKAG
Ligand information
>8p16 Chain 4 (length=26) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaaggagguauuaaaugugggaauuc
..........................
Receptor-Ligand Complex Structure
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PDB8p16 The compensatory mechanism of a naturally evolved E167K RF2 counteracting the loss of RF1 in bacteria
Resolution2.77 Å
Binding residue
(original residue number in PDB)		G137 E140 V202 S205 G210 R212 R213 H214 T215
Binding residue
(residue number reindexed from 1)		G134 E137 V199 S202 G207 R209 R210 H211 T212
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016149 translation release factor activity, codon specific
Biological Process
GO:0006412 translation
GO:0006415 translational termination
GO:0075523 viral translational frameshifting
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8p16, PDBe:8p16, PDBj:8p16
PDBsum8p16
PubMed
UniProtP07012|RF2_ECOLI Peptide chain release factor RF2 (Gene Name=prfB)

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