Structure of PDB 8fni Chain 6 Binding Site BS02

Receptor Information
>8fni Chain 6 (length=453) Species: 5691 (Trypanosoma brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHLSARNIATEALQMKKLHQERGGNPMLAQQARRVLFATSIAGQNLDARS
VALLLNTAVYFGMESDAKLVRECIDYCLKNDKLITVDVLPIVVTACATLK
SRDAREVIEMQAQKAARNAKFLDAKDVTNIISAFSKTGINHEKLFAFLSR
RVQTLARVGEFEAAHLVILANAFSRLRYRDKFLFGAIARRAMSLRERVTV
NELVPLIVAFSKIGLKDPKLSKRFATKAMEYVDQMNAEQVASMFMAFAYF
GIRYDQLFGVLTNRAVELIDEFNAQYISTTLNAFQRIGINNPELFDNLAE
RALAVVQDHDARDISKTVTALAHFGLKDEELFKRLASHAASIADQFDAMG
LVNTAHAFARTNFLQQDMAVALSERSVYVCRLLDAGETRRLLWALAKFQV
RDPKILTPVFNRCLALHYDFFADPTGSEEIEEIFDFYGPNFCPPLYQLYI
SRG
Ligand information
Receptor-Ligand Complex Structure
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PDB8fni Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		R208 R215 F240 R247
Binding residue
(residue number reindexed from 1)		R150 R157 F182 R189
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
Biological Process
GO:0000963 mitochondrial RNA processing
GO:0006396 RNA processing
GO:0044528 regulation of mitochondrial mRNA stability
GO:0090615 mitochondrial mRNA processing
GO:1900864 mitochondrial RNA modification
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0031019 mitochondrial mRNA editing complex
GO:0035770 ribonucleoprotein granule

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fni, PDBe:8fni, PDBj:8fni
PDBsum8fni
PubMed37410820
UniProtQ57ZX7

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