Structure of PDB 8fnc Chain 6 Binding Site BS02

Receptor Information
>8fnc Chain 6 (length=452) Species: 5691 (Trypanosoma brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VSHLSARNIATEALQMKKLHQERGGNPMLAQQARRVLFATSIAGQNLDAR
SVALLLNTAVYFGMESDAKLVRECIDYCLKNDKLITVDVLPIVVTACATL
KSRDAREVIEMQAQKAARNAKFLDAKDVTNIISAFSKTGINHEKLFAFLS
RRVQTLARVGEFEAAHLVILANAFSRLRYRDKFLFGAIARRAMSLRERVT
VNELVPLIVAFSKIGLKDPKLSKRFATKAMEYVDQMNAEQVASMFMAFAY
FGIRYDQLFGVLTNRAVELIDEFNAQYISTTLNAFQRIGINNPELFDNLA
ERALAVVQDHDARDISKTVTALAHFGLKDEELFKRLASHAASIADQFDAM
GLVNTAHAFARTNFLQQDMAVALSERSVYVCRLLDAGETRRLLWALAKFQ
VRDPKILTPVFNRCLALHYDFFADPTGSEEIEEIFDFYGPNFCPPLYQLY
IS
Ligand information
Receptor-Ligand Complex Structure
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PDB8fnc Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		R208 Q211 R215 F240 R247
Binding residue
(residue number reindexed from 1)		R151 Q154 R158 F183 R190
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
Biological Process
GO:0000963 mitochondrial RNA processing
GO:0006396 RNA processing
GO:0044528 regulation of mitochondrial mRNA stability
GO:0090615 mitochondrial mRNA processing
GO:1900864 mitochondrial RNA modification
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0031019 mitochondrial mRNA editing complex
GO:0035770 ribonucleoprotein granule

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fnc, PDBe:8fnc, PDBj:8fnc
PDBsum8fnc
PubMed37410820
UniProtQ57ZX7

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