Structure of PDB 6lqu Chain 5G Binding Site BS02

Receptor Information
>6lqu Chain 5G (length=282) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLRRQARERREYLYRKAQELQDSQLQQKRQIIKQALAQGKPLPKELAEDE
SLQKDFRYDQSLKQVDDEYAATSGIMDPRIIVTTSRDPSTRLSQFAKEIK
LLFPNAVRLNRGNYVMPNLVDACKKSGTTDLVVLHEHRGVPTSLTISHFP
HGPTAQFSLHNVVMRHDIINAGNQSEVNPHLIFDNFTTALGKRVVCILKH
LFNAGPKKDSERVITFANRGDFISVRQHVYVRTREGVEIAEVGPRFEMRL
FELRLGTLENKDADVEWQLRRFIRTANKKDYL
Ligand information
>6lqu Chain SA (length=1242) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagauaguuaucugguugauccugccaguagucauaugcuugucucagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaaggcucau
uaaaucaguuaucguuuauuugauaguuccaugguauaacugugguaauu
cuagagcuaauacaugcuaaucucgacccuuuggaagagauguauuuauu
agaucaaugucuucggacucuuugaugaaauaacuuuucgaaucgcaugg
ccuugugcuggcgaugguucauucaaauuucugcccuaucaacuuucgau
gguaggauaguggccuaccaugguuucaacggguaacggggaauaagggu
ucgauuccggagagggagccugagaaacggcuaccacauccaaggaaggc
agcaggccaaauuacccaauccuaauucagggagguagugacaauaaaua
acgauacagggcccauucgggucuuguaauuggaaugaguacaauguaaa
uaccuuaacgaggaacaauuggagggcaagucuggugccagcagccgcgg
uaauuccagcuccaauagcguauauuaaaguuguugcaggcucguaguug
aacuuagggacggucgggggcaucaguauucaauugucagaggugaaauu
cuuggauuuauugaagacuaacuacugcgaaagcauuugccaaggacguu
uucauuaaucaagaacgaaaguuaggggaucgaagaugaucagauaccgu
cguagucuuaacuggggggaguauggucgcaaggcugaaacuuaaaggaa
uugacggaagggcaccaccaggaguggagccugcggcucaacacggggaa
acucaccagguccagacacaauaaggauugacauucuugauuuugugggu
gguggugcauugaugcccuuguucugggccacgcgcgcuacacugacgga
gccagcgagucuaaccuuggccgagaggucuugguaaucuugugaaacuc
cgucgugcuggggauauucaacgaggaauuccuaguaagcgcaagucauc
agcuugcguugauuacgucccugcccuuuguacacaccgcccgucgcuag
uaccgauugaauggcuuagugaggccucaggaucugcuuagagaaggggg
caacuccaucucagagcggagaauuuggacaaacuuggucauuuagagga
acuaaaagucguaacaagguuuccguaggugaaccugcggaa
............................<<<<.<<<<<<........<<<
.<<...<<....<<....<<..........>>...>>.>>.....<<<..
.....<<<..<<..<<....<<<..........<.....<<.<<......
.>>.>>......>.......<<<<............>>>>.....<<<<<
...<<<<..............>>>>...>>>>>.........<<<<...<
<.....>>..>>>>....>>>...>>>>..>>>.<<<....<<<....<<
<<<<<<.......>>>>>>>>>>>......>>>.....<<..........
.....>>..>>>.<<.<<<..........>>>.>>.<.<<....>>.>..
..>>>>>......<<<....<<<.....>>>..>>>..............
.<<<<<<<.<<<<<....>>>>>.>>>.>>>>......<<..<.......
....>..>>.........<<<<<<.......<<<....>>>.........
.........>>>>>>..>>>>>>>>>>.........<..<.<<...<<<.
......<<<<<<.<<...<<<<..<<..<<<<<<.<...<<<......>>
>......>.>>>>>>..>>.......<<....>>...>>>>..>.>>>>.
>>>...>>>...>>.>......<<<<<...<...<<<<.........>>>
>...>>>>>>...>....................<<.........>>...
..<<<<<<<<<<<<..<<.<<<<<<..<<<.<<<<...............
........<<.<....<<<<<........<.....>......>>>>>...
...<<<........>>>...>.>>.......>>>>.>>>.....<<<<<<
<............<<<..<<<<....>>>>..>>>............>>>
>>>>.......................>>>>>>....<<<<<<<<.....
..>>>>>>>>......>>...>>>>>>>............>>>>>..<<<
..<<....<.<<<..<.<<<..<.<<......<<<<<<<.<<<<.<<<<.
...>>>>.>>>>.>>>>>>>......>>.>..>>>.>..>>>>....>>.
.>>>................<<<<<<<<<....>>>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6lqu Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		K40 S93 R94 S97 Q102 K105 R116 N118 R119 G120 N121 Y122 V123 H143 E144 H145 R146 G147 S166 H174 N181 Q182 S183 E184 V185 F259 Q276 L277 R278 R279 I281 R282 T283 K287
Binding residue
(residue number reindexed from 1)		K40 S85 R86 S89 Q94 K97 R108 N110 R111 G112 N113 Y114 V115 H135 E136 H137 R138 G139 S158 H166 N173 Q174 S175 E176 V177 F251 Q268 L269 R270 R271 I273 R274 T275 K279
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0030515 snoRNA binding
GO:0042134 rRNA primary transcript binding
GO:0043047 single-stranded telomeric DNA binding
Biological Process
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:0034457 Mpp10 complex
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6lqu, PDBe:6lqu, PDBj:6lqu
PDBsum6lqu
PubMed32943522
UniProtP53941|IMP4_YEAST U3 small nucleolar ribonucleoprotein protein IMP4 (Gene Name=IMP4)

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