Structure of PDB 6ke6 Chain 5D Binding Site BS02

Receptor Information
>6ke6 Chain 5D (length=235) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKLVHDVQKKQHRERSQLTSRSRYGFLEKHKDYVKRAQDFHRKQSTLKVL
REKAKERNPDEYYHAMHSRKTDAKGLLISSRHGDEEDESLSMDQVKLLKT
QDSNYVRTLRQIELKKLEKGAKQLMFKSSGNHTIFVDSREKMNEFTPEKF
FNTTSEMVNRSENRLTKSIMPKESLDKKKLKKFKQVKQHLQRETQLKQVQ
QRMDAQRELLKKGSKKKIVDSSGKISFKWKKQRKR
Ligand information
>6ke6 Chain 5A (length=522) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugcgaaagcagugaagacaaguggcuugucguucguuaaaauggccucgu
caaacgguggagagagucgcuaggugaucgucagaucugccuagucucua
uacagcguguuuaauugacauggguugaugcguauugagagauacaauuu
gggaagaaauucccagaguguguuucuuuugcguuuaaccugaacagucu
caucgugggcaucuugcgauuccauuggugagcagcgaaggauuuggugg
auuacuagcuaauagcaaucuauuucaaagaauucaaacuugggggaaug
ccuuguugaauagccggucgcaagacugugauucuucaaguguaaccucc
ucucaaaucagcgauaucaaacguaccaccgugaaacaccgggguaucug
uuugguggaaccugauuagaggaaacucaaagagugcuaugguaugguga
cggagugcgcuggucaagaguguaaaagcuuuuugaacagagagcauuuc
cggcagcagagauuucagcugu
<<<....>>>..<<<<<<<<<<.>>>>>>>.>>>..............<<
<<<<<<.<<...<<<<..<<<<<<<<<<<....>>>>.>>>>>>>>>>>.
..>>.>>>......>>>>>..<<<<<..........<<<<<<<<<<.<<<
<<<<<....>>>>>>>>.>>>>>>>>>>........>>>>>.......<<
<<<<<<<<<...........>>>>>.>>>>>>..................
.......<<<...>>>.........................<<<<<...<
<<<<<..<<<<...<<<<<....>>>>>.>.>>>..>>>>.>>..>>>>>
.....<<<<<<...<<<<<<<<<<<<<.<<<........>>>>>>>.>.>
>>>>>>>....>>>>>>.................................
<<<<<<<<.<<<.<<<<<<<<......>>>>.>>>>.>>>...>>>>.>>
>>.<<<<.<<<..>>>.>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ke6 3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome
Resolution3.4 Å
Binding residue
(original residue number in PDB)		V50 R82 G84 S90 L91 S92 M93 Y106 V107 F146 T155 N160 S189 K192 K193 K196 Q200 R217 L224 G228 S229 K230 K231 K232 F242
Binding residue
(residue number reindexed from 1)		V49 R81 G83 S89 L90 S91 M92 Y105 V106 F145 T154 N159 S174 K177 K178 K181 Q185 R202 L209 G213 S214 K215 K216 K217 F227
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0006412 translation
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005732 sno(s)RNA-containing ribonucleoprotein complex
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6ke6, PDBe:6ke6, PDBj:6ke6
PDBsum6ke6
PubMed
UniProtP34247|UTP11_YEAST U3 small nucleolar RNA-associated protein 11 (Gene Name=UTP11)

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