Structure of PDB 6lqr Chain 5C Binding Site BS02

Receptor Information
>6lqr Chain 5C (length=458) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KERENQNKFERSTYTNNQTKDKKLRAGLKKIDEQYKKAVSSAAATDYLLP
ESNGYLEPENELEKTFKVQQSEIKSSVDVSTANKALDLSLKEFGPYHIKY
AKNGTHLLITGRKGHVASMDWRKGQLRAELFLNETCHSATYLQNEQYFAV
AQKKYTFIYDHEGTELHRLKQHIEARHLDFLPYHYLLVTAGETGWLKYHD
VSTGQLVSELRTKAGPTMAMAQNPWNAVMHLGHSNGTVSLWSPSMPEPLV
KLLSARGPVNSIAIDRSGYYMATTGADRSMKIWDIRNFKQLHSVESLPTP
GTNVSISDTGLLALSRGPHVTLWKDALKLSGDSKPCFGSMGGNPHRNTPY
MSHLFAGNKVENLGFVPFEDLLGVGHQTGITNLIVPGAGEANYDALELNP
FETKKQRQEQEVRTLLNKLPADTITLDPNSIGSVDKRSSTIRLNAKDLDV
IEEALSRF
Ligand information
>6lqr Chain 5A (length=192) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugcgaaagcaguugaagacaaguggcuugucguucguuaauggccucguc
cagcgaaggauuugguggauuacuagcuaauagcaaucuaggaaacucaa
agagugcuaugguauggugacggagugcgcuggucaagaguguaaaagcu
uuuugaacagagagcauuuccggcagcagagauuucagcugu
<<<....>>>...<<<<<<<<<<.>>>>>>>.>>>...............
.........................<<<...>>>................
....................<<<<.<<<.<<<.<<<<<<<<......>>>
>.>>>>.>>>...>>>..>>>><<<<<.<<<..>>>.>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6lqr Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Resolution8.6 Å
Binding residue
(original residue number in PDB)		K82 F84 K85 Q164 H179 P316 H337 G356 S357 G359 G360 A374 K422 R425
Binding residue
(residue number reindexed from 1)		K64 F66 K67 Q146 H161 P298 H319 G338 S339 G341 G342 A356 K404 R407
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0030688 preribosome, small subunit precursor
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6lqr, PDBe:6lqr, PDBj:6lqr
PDBsum6lqr
PubMed32943522
UniProtP40055|UTP7_YEAST U3 small nucleolar RNA-associated protein 7 (Gene Name=UTP7)

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