Structure of PDB 5zwm Chain 5 Binding Site BS02

Receptor Information

>5zwm Chain 5 (length=103) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SRHQFDLIMCLKQPGVQTGLLCEKCDGKCPICDSYVRPKRKVRVCENCSF
GKQAKNCIICNLNVGVNDAFYCWECCRLGKDKDGCPRILNLGSNRLDRHF
EKK

Ligand information

InChI=1S/Zn/q+2

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Zn

Name

ZINC ION

PDB chain

5zwm Chain 5 Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	5zwm Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Resolution	3.4 Å
Binding residue (original residue number in PDB)	C11 C49 C86
Binding residue (residue number reindexed from 1)	C10 C48 C85
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0008270	zinc ion binding

	Biological Process
GO:0000245	spliceosomal complex assembly
GO:0000398	mRNA splicing, via spliceosome
GO:0006397	mRNA processing
GO:0008380	RNA splicing
GO:0009410	response to xenobiotic stimulus
GO:1903241	U2-type prespliceosome assembly

	Cellular Component
GO:0005634	nucleus
GO:0005681	spliceosomal complex
GO:0005684	U2-type spliceosomal complex
GO:0005686	U2 snRNP
GO:0071011	precatalytic spliceosome

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:5zwm, PDBe:5zwm, PDBj:5zwm
PDBsum	5zwm
PubMed	29794219
UniProt	Q06835\|RDS3_YEAST Pre-mRNA-splicing factor RDS3 (Gene Name=RDS3)

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