Structure of PDB 6m62 Chain 4 Binding Site BS02

Receptor Information
>6m62 Chain 4 (length=516) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ILQESVLNKYRTAGQIAQTALKYVTSLINDSYHSKTTQRQLTVPELCLLT
DSFILTRLEQYYKNKVNERGIAIPTTIDIDQISGGWCPEIDDTQNLLNWN
KGKDSTFASSVTGTLRPGDLVKITLGVHIDGYTSEVSHTMVIYPVDETKP
ILQPTGPLLGGKADAVAAAHIAMETVVALLACALTPEKLPASLGGTSSGI
TGQLIRTIVDTIARSYNCGVVPGSRVRRIRRFLAGQNEGIVAEREYKGVV
WTESHQEADLLSAIPSDDFVVQSGEVYLIDLKMASLEHCTKKGLVTLETV
DSYTGKSHKAGELIARPGAYVRDFAQTHILKLKTSRQLLTKIDKQGVYPF
KLSHLSSNFPFVHENEEELQSLKKDLKSFRLGMSEISNNYLCVESPIQIA
RWVPWDHILKATNPLPLPKLGVSAIKLKSLMNSTKESISLPVARECNTIV
LCDSSVSTTDRPELLRLTGGSKTCQPSWIHSQHELNPQDSIVQGIFQLAT
LAKDLLLKETQPMKQK
Ligand information
>6m62 Chain 2 (length=158) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaacuuucaacaacggaucucuugguucucgcaucgaugaagaacgcagc
gaaaugcgauacguaaugugaauugcagaauuccgugaaucaucgaaucu
uugaacgcacauugcgccccuugguauuccagggggcaugccuguuugag
cgucauuu
.........................................<<<<<<.<<
.....>>>.....(.<<<......>>..............>>>..)...>
>>....<<.....>><<<<<<<<<....>>>>>>>>>.............
........
Receptor-Ligand Complex Structure
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PDB6m62 Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		S347 H348 K349 N490 K493
Binding residue
(residue number reindexed from 1)		S307 H308 K309 N432 K435
Enzymatic activity
Enzyme Commision number 3.-.-.-
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0000055 ribosomal large subunit export from nucleus
GO:0006508 proteolysis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0030687 preribosome, large subunit precursor

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Molecular Function
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Cellular Component
External links
PDB RCSB:6m62, PDBe:6m62, PDBj:6m62
PDBsum6m62
PubMed32719344
UniProtQ03862|ARX1_YEAST Probable metalloprotease ARX1 (Gene Name=ARX1)

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